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The same references list a pH around 5.7, with a range of 4.5 to 7.0

Formula A with a carboxylic acid activator in the presence of N-(3-Dimethylaminopropyl)-N'- ethylcarbodiimide hydrochloride in a polar aprotic solvent selected from N,N- dimethylformamide, dimethyl sulfoxide and tetrahydrofuran, preferably N,N- dimethylformamide, and b) reacting the reaction mixture of step a) with a compound of Formula B

This type of synergistic approach often delivers faster, more noticeable results than single-ingredient products, making it worth considering for those serious about addressing hyperpigmentation concerns

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